This paper will begin with a comprehensive literature review of the nursing shortage in the sub-Saharan African region. The global nursing crisis is explored with a focus on the economics of nursing, challenges presented by the nursing shortage, interventions to increase nursing capacity, and partnerships that have been implemented to achieve this goal. The nursing shortage in selected sub-Saharan African countries is analyzed from a policy perspective using Fawcett and Russell’s Conceptual Model of Nursing and Health Policy (2005). Then, McLaughlin and McLaughlin's Policy Analysis Process (2008) is used to identify, analyze, evaluate, and make recommendations to create health policy. The primary thrust is to advocate for sustainable interventions that will assist in alleviating the nursing shortage in selected sub-Saharan African countries.